Prolonged fasting — going without food for more than 24 hours — has gained significant attention in recent years for its potential health benefits. Unlike intermittent fasting, which involves daily time-restricted eating, prolonged fasting can last from 36 hours to several days. But what does science really say? Here are 7 critical things you need to know about prolonged fasting and why it might be the reset your body needs.
1. Triggers Autophagy: Cellular Housekeeping
One of the most powerful effects of prolonged fasting is autophagy — your body’s way of cleaning out damaged cells and regenerating new ones. This process can reduce inflammation, prevent disease, and even slow down the aging process.
2. Supports Weight Loss and Fat Burning
When you’re fasting, your body switches from burning glucose to burning stored fat for energy — a metabolic state called ketosis. This leads to faster fat loss, especially around the belly.
3. Improves Insulin Sensitivity
Fasting for extended periods allows insulin levels to drop significantly, making your cells more responsive to it. This can be especially beneficial for those with insulin resistance or prediabetes.
4. Boosts Mental Clarity and Brain Function
Many people report improved focus and mental clarity during prolonged fasts. This is because fasting increases the production of brain-derived neurotrophic factor (BDNF), a protein that supports brain health and learning.
5. Reduces Inflammation
Chronic inflammation is at the root of many health problems, from arthritis to heart disease. Fasting has been shown to reduce inflammatory markers in the blood, giving your immune system a break.
6. May Promote Longevity
Animal studies suggest that prolonged fasting can extend lifespan and delay the onset of age-related diseases. While more human research is needed, early results are promising.
7. Requires Caution and Preparation
Prolonged fasting isn’t for everyone. It’s essential to consult a healthcare provider before attempting a fast longer than 24 hours, especially if you have medical conditions, take medications, or are underweight.
Final Thoughts
Prolonged fasting offers many proven benefits, from cellular regeneration to mental clarity and weight loss. However, it should be approached with care and knowledge. If done correctly, it can be a powerful tool to reset your health and promote long-term wellness.
